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12 Dec 2011

Human Growth Hormone is synthesized by somatotroph cells which are found in the anterior lobe of pituitary gland. This hormone is build up of polypeptide chain of 191 amino acids and has a molecular weight of 22,000. Although structural similarities exist between growth hormone from various species, only primate growth hormone is found active in humans.

Biochemistry of HGH is quite complex. Although there is plenty of HGH in our young age.  But as you become old, release of Hormones from the pituitary gland becomes slow. The main purpose of HGH Human Growth Hormone is to stimulate the liver and other tissues for the production of IGF-1. IGF-1 tissue possesses autocrine properties. During the developmental stages, HGH is quite essential for the promotion of linear growth, it also stimulates the growth of muscles and bones. HGH also increases the protein synthesis and influences the metabolism of bones and minerals.

Another name of Growth Hormone is somatropin. Growth Hormone is a hormone which stimulates the cell production in humans and other animals. GH release can be stimulated by sleep, exercise, dietary protein, hypoglycemia, and estradiol. Inhibitors of secretion of GH are glucocorticoids and dietary carbohydrate.

The level and amount of GH secretion change throughout the whole life. The Basal levels are at the highest level in the childhood. The frequency of peaks is at its maximum level during the pubertal growth spurt. Basal levels and the amplitude of frequency peaks decrease through all the adult life.

It is proved that Aging factor is associated and initiated by the low production of HGH by the pituitary gland. So our key focus should be to adopt ways to increase the levels of HGH hormones so that symptoms such as forgetfulness, unexplained gain of weight, decrease in the sex drive and diseases of joints can be avoided.


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